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ON BRAIN ENERGY USE:

Herculano-Houzel S, Rothman DL (2022) From a demand-based to a supply-limited framework of brain metabolism. Frontiers in Integrative Neuroscience 16, 818685.
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Ventura-Antunes L, Dasgupta OM, Herculano-Houzel S (2022) Resting rates of blood flow and glucose use per neuron are proportional to number of endothelial cells available per neuron across sites in the rat brain. Frontiers in Integrative Neuroscience 16, 821850.

Ventura-Antunes L, Herculano-Houzel S (2022) Energy availability per neuron is constrained by capillary density in the mouse brain. Frontiers in Integrative Neuroscience 16, 760887.

Herculano-Houzel S (2011) Scaling of brain metabolism with a fixed energy budget per neuron: implications for neuronal activity, plasticity and evolution. PLoS One 6: e17514. 

ON AGING, LONGEVITY, AND OTHER TIME-RELATED ASPECTS OF LIFE:

Herculano-Houzel S (2019) Longevity and sexual maturity vary across species with number of cortical neurons, and humans are no exception. J Comp Neurol 527, 1689-1705. ​

Herculano-Houzel S (2019) Life history changes accompany increased numbers of cortical neurons: a new framework for understanding human brain evolution. Prog Brain Res 250, 179-216. ​

Herculano-Houzel S (2015) Decreasing sleep requirement with increasing numbers of neurons as a driver for bigger brains and bodies in mammalian evolution. Proc Royal Soc B 282, 20151853. ​​

Fonseca-Azevedo K, Herculano-Houzel S (2012) Metabolic constraint imposes trade-off between body size and number of brain neurons in human evolution. Proc Natl Acad Sci USA 109, 18571-18576. 

Morterá P, Herculano-Houzel S (2012) Age-related neuronal loss in the rat brain starts at age 3 months. Frontiers in Neuroanatomy 6, 45.  

ON THE IMPLICATIONS OF MORE NEURONS FOR COGNITION AND BEHAVIOR:

Ströckens F, Neves K, Kirchen S, Schwab C, Herculano-Houzel S, Güntürkün O (2022) High associative neuron numbers could drive cognitive performance in corvid species. Journal of Comparative Neurology, in press.

Jacob J, Kent M, Bensom-Amram S, Herculano-Houzel S, Raghanti MA, Pioppert E, Drake J, Hindi B, Natale NR, Daniele S, Fanelli R, Miller A, Landis T, Gilbert A, Johnson S, Lai A, Hyer M, Rzucidlo A, Anchor C, Gehrt S, Lambert K (2021) Cytoarchitectural characteristics associated with cognitive flexibility in raccoons. Journal of Comparative Neurology 529, 3375-3388.

​Neves K, Guercio GD, Anjos-Travassos Y, Costa S, Perozzo A, Montezuma K, Herculano-Houzel S, Panizzutti R (2020) Lack of correlation between number of neurons and behavioral performance in Swiss mice. Neurosci Lett  735, 135202.            

Herculano-Houzel S (2018) Embodied (embrained?) cognitive evolution, at last! Comp Cognition Behav Rev 13, 91-94.

Herculano-Houzel S (2017) Numbers of neurons as biological correlates of cognitive capability. Curr Opin Behav Sci 16, 1-7.

Herculano-Houzel S, Kaas JH, de Oliveira-Souza R (2016) Corticalization of motor control in primate evolution. Journal of Comparative Neurology524, 448-455.          

​Gabi M, Neves K, Masseron C, Ventura-Antunes L, Ribeiro P, Torres L, Mota B, Kaas JH, Herculano-Houzel S (2016) No expansion in numbers of prefrontal neurons in primate and human evolution. Proc Natl Acad Sci USA 113, 9617-9622.          

ON CORTICAL FOLDING:

Mota B, Dos Santos SE, Ventura-Antunes L, Jardim-Messeder D, Neves K, Siqueira R, Noctor S, Lambert K, Bertelsen MF, Manger PR, Sherwood C, Kaas JH, Herculano-Houzel S (2019) White matter volume and white/gray matter ratio in different mammalian species as a consequence of the universal scaling of cortical folding. PNAS 116, 15253-15261. 
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Mota B, Herculano-Houzel S (2016) Response to comments on “Cortical folding scales universally with surface area and thickness, not number of neurons”. Science 351, 826.                

Mota B, Herculano-Houzel S (2015) Cortical folding scales universally with cortical surface area and thickness, not number of neurons. Science 349, 74-77.           ​

ON DIFFERENT FUNCTIONAL SYSTEMS AND CORTICAL AREAS:

Gabi M, Neves K, Masseron C, Ventura-Antunes L, Ribeiro P, Torres L, Mota B, Kaas JH, Herculano-Houzel S (2016) No expansion in numbers of prefrontal neurons in primate and human evolution. Proc Natl Acad Sci USA 113, 9617-9622. 

Herculano-Houzel S, Kaas JH, de Oliveira-Souza R (2016) Corticalization of motor control in primate evolution. Journal of Comparative Neurology524, 448-455.

Ribeiro PFM, Manger PR, Catania K, Kaas JH, Herculano-Houzel S (2014) Greater addition of neurons to the olfactory bulb than to the cerebral cortex of insectivores but not rodents or primates. Front Neuroanat 8, 23. 

Herculano-Houzel S, Watson C, Paxinos G (2013) Distribution of neurons in functional areas of the mouse cerebral cortex reveals quantitatively different cortical zones. Frontiers in Neuroanatomy 7, 35. 

Ribeiro PFM, Ventura-Antunes L, Gabi M, Mota B, Grinberg LT, Farfel JM, Ferretti REL, Leite REP, Jacob Filho W, Herculano-Houzel S (2013) The human cerebral cortex is neither one nor many: Neuronal distribution reveals two quantitatively different zones in the grey matter, three in the white matter, and explains local variations in cortical folding. Frontiers in Neuroanatomy 7, 28. 

Collins CE, Leitch DB, Wong P, Kaas JH, Herculano-Houzel S (2013) Faster scaling of visual neurons in cortical areas relative to subcortical structures in primate brains. Brain Structure and Function 218: 805-816. 

Wong P, Peebles JK, Asplund CL, Collins CE, Herculano-Houzel S, Kaas JK (2013) Faster scaling of auditory neurons in cortical areas relative to subcortical structures in primate brains. Brain Behavior and Evolution 81, 209-218. 

​Herculano-Houzel S (2010) Coordinated scaling of cortical and cerebellar numbers of neurons. Frontiers in Neuroanatomy 4, 12.  

ON NUMBERS OF NEURONS IN DIFFERENT SPECIES:

Herculano-Houzel S, Cunha F, Reed JL, Kaswera-Kyamakya C, Gillissen E, Manger PR (2020) Microchiropterans have a diminutive cerebral cortex, not an enlarged cerebellum, compared to megachiropterans and other mammals. Journal of Comparative Neurology 528, 2978-2993. ​

​Jardim-Messeder D, Lambert K, Noctor S, Marques Pestana F, DeCastro Leal ME, Bertelsen MF, Alagaili AN, Mohammad OB, Manger PR, Herculano-Houzel S (2017) Dogs have the most neurons, though not the largest brain: Trade-off between body mass and number of neurons in the cerebral cortex of large carnivoran species. Front Neuroanat 11, 118. ​

Dos Santos SE, Porfirio J, Da Cunha FB, Manger PR, Tavares W, Pessoa L, Raghanti MA, Sherwood CC, Herculano-Houzel S (2017) Cellular scaling rules for the brain of marsupials: not as “primitive” as expected. Brain Behav Evol 89, 48-63. ​

​Olkowicz S, Kocourek M, Lucan RK, Portes M, Fitch WT, Herculano-Houzel S, Nemec P (2016) Birds have primate-like numbers of neurons in the telencephalon. Proc Natl Acad Sci USA 113, 7255-7260.

Ngwenya A, Patzke N, Manger PR, Herculano-Houzel S (2016) Continued growth of the central nervous system without mandatory addition of neurons in the Nile crocodile (Crocodylus niloticus). Brain Behav Evol 87, 19-38. 

Herculano-Houzel S, Catania K, Manger PR, Kaas JH (2015) Mammalian brains are made of these: A dataset on the numbers and densities of neuronal and non-neuronal cells in the brain of glires, primates, scandentia, eulipotyphlans, afrotherians and artiodactyls, and their relationship with body mass. Brain Behav Evol 86, 145-163. 

Kazu RS, Maldonado J, Mota B, Manger PR, Herculano-Houzel S (2014) Cellular scaling rules for the brains of Artiodactyla. Front Neuroanat 8, 128. 

​Herculano-Houzel S, Avelino-de-Souza K, Neves K, Porfírio J, Messeder D, Calazans I, Mattos L, Maldonado J, Manger PM (2014) The elephant brain in numbers. Front Neuroanat 8, 46.

Neves Jr K, Ferreira FM, Tovar-Moll F, Gravett N, Bennett NC, Kaswera C, Gilissen E, Manger PR, Herculano-Houzel S (2014) Cellular scaling rules for the brains of Afrotheria. Front Neuroanat 8, 5.   

​Herculano-Houzel S, Ribeiro PFM, Campos L, da Silva AV, Torres LB, Catania KC, Kaas JH (2011) Updated neuronal scaling rules for the brains of Glires (rodents/lagomorphs). Brain Behav Evol 78, 302-314. 

​Herculano-Houzel S, Kaas JH (2011) Gorilla and orangutan brains conform to the primate scaling rules: Implications for hominin evolution. Brain Behav Evol 77: 33-44. 

Gabi M, Collins CE, Wong P, Kaas JH, Herculano-Houzel S (2010) Cellular scaling rules for the brain of an extended number of primate species. Brain, Behavior and Evolution 76, 32-44.            

Burish MJ, Peebles JK, Tavares L, Baldwin M, Kaas JH, Herculano-Houzel S (2010) Cellular scaling rules for primate spinal cords. Brain, Behavior and Evolution 76, 45-59. 

Herculano-Houzel S (2009) The human brain in numbers: a linearly scaled-up primate brain. Frontiers In Human Neuroscience 3, 31. 

Sarko DK, Catania KC, Leitch DB, Kaas JH, Herculano-Houzel S (2009) Cellular scaling rules of insectivore brains. Frontiers in Neuroanatomy 3, 8. 

Azevedo FAC, Carvalho LRB, Grinberg LT, Farfel JM, Ferretti REL, Leite REP, Jacob Filho W, Lent R, Herculano-Houzel S (2009). Equal numbers of neuronal and non-neuronal cells make the human brain an isometrically scaled-up primate brain. Journal of Comparative Neurology 513, 532-541. 

Herculano-Houzel S, Collins C, Wong P, Kaas JH (2007) Cellular scaling rules for primate brains. Proceedings of the National Academy of Sciences USA 104, 3562-3567. 

​Herculano-Houzel S, Mota B, Lent R (2006) Cellular scaling rules for rodent brains. Proceedings of the National Academy of Sciences USA 103, 12138-12143.

ON GLIAL CELLS:

Dos Santos SE, Botelho L, Medeiros M, Porfirio J, Tavares W, Pessoa L, Grinberg L, Leite R, Ferretti-Rebustini R, Farfel JM, Jacob Filho W, Noctor SC, Lambert K, Raghanti MA, Sherwood CC, Kaas JH, Manger PR, Herculano-Houzel S (2020) Similar microglial cell densities across brain structures and mammalian species: Implications for brain tissue function. Journal of Neuroscience 40, 4622-4643.

​Herculano-Houzel S, Dos Santos S (2018) You do not mess with the glia. Neuroglia 1, 193-219.

Von Bartheld CS, Bahney J, Herculano-Houzel S (2016) The search for true numbers of neurons and glial cells in the human brain: A review of 150 years of cell counting. J Comp Neurol 524, 3865-3895. 

Mota B, Herculano-Houzel S (2014) All brains are made of this: a fundamental building block of brain matter with matching neuronal and glial masses. Front Neuroanat 8, 127. 

Herculano-Houzel S (2014) The glia/neuron ratio: How it varies uniformly across brain structures and species and what that means for brain physiology and evolution. Glia 62, 1377-1391. 

ON CELL COUNTING METHODS:

Herculano-Houzel S, Kaas JH, Miller D, Von Bartheld CS (2015) How to count cells: the advantages and disadvantages of the isotropic fractionator compared with stereology. Cell Tissue Research 360, 29-42. 

​Herculano-Houzel S, Lent R (2005). Isotropic fractionator: a simple, rapid method for the quantification of total cell and neuron numbers in the brain. Journal of Neuroscience 25, 2518-2521.